Production Of Transgenic Animals Notes
There are many ways to produce transgenic animals.
Production of transgenic animals notes. The transgenic expression is not only used to breed animals which have specific traits but also to breed animals that are lacking specific genes This technique is called as knockout or gene. Then they are inserted into a blastocyst and implanted into a hosts uterus to grow normally. To yield industrial as well as consumer product To research human diseases To produce pharmaceutical products and tissue for implantation.
A transgenic animal is one that carries a foreign gene that has been deliberately inserted into its genome. The first transgenic animal was produced in 1983 when genes for human growth hormone were introduced into mice. The three main ways of producing transgenic animals are pronuclear manipulation embryonic stem ES cell manipulation and.
Let us discuss a few of them here. Transgenic animals can be used to produce valuable products. The development of transgenic animals has been part of biotechnology research which has been expanding rapidly.
The foreign genes must be transmitted through the germ line so that every cell including germ cells of the animal contains the same modified genetic material. Transgenic mice are developed by injecting DNA into the oocytes or 1-2 celled embryos taken from female mice. Trans-genesis is important for improving the quality and quantity of milk meat eggs and wool production besides creating drug resistant animals.
43 Creation of the transgenic animal A number of methods are currently in use for the creation of transgenic animals. Transgenic organisms are organisms that are injected with foreign DNA. The foreign gene is constructed using recombinant DNA methodology.
The medical and biotechnological uses of animal cloning are almost innumerable as many diseases have been eradicated thanks to the production of these transgenic animals. Biotechnology for Sustainable Agriculture 2018. Example- Transgenic rats rabbits pigs sheep etc.